Senior Research Associate for Neuroscience - CA in San Diego, CA at Apex Life Sciences

Date Posted: 2/1/2018

Job Snapshot

Job Description

Job Description:

  • Our Client is seeking a highly motivated Senior Research Associate to join our growing Neuroscience and Imaging Team.
  • The successful candidate will have a background in cell and molecular biology and an interest in drug discovery.
  • He/she will play a key role in a small, highly dispersed team supporting our efforts to develop novel therapeutics for neurodegenerative diseases. 
  • This role will involve designing, executing, and evaluating cell-based assays to answer focused scientific questions about relevant targets in neurodegenerative diseases.
  • The ideal candidate will have experience working with human neuronal and glial cell lines and iPSC-derived cells, biochemical analysis of target engagement, and a degree in neuroscience or biology.
  • The candidate should be able to work independently in the wet lab, help research and develop new protocols, and quickly learn new techniques. 

Responsibilities will include, but are not limited to, the following: 

  • Applying a suite of cell and molecular biology techniques to generate stable cell lines and challenge them using disease-appropriate stimuli. 
  • Growing in vitro cellular models of disease, treating with compounds, processing cells for downstream analysis. 
  • Performing SDS-PAGE and native immunoblot analysis of protein aggregation. 
  • Performing protein and gene expression analysis using ELISA, MSD, and qPCR. 
  • Performing flow cytometry and microscopy. 
  • Assist in handling screening-related information, such as internal compound requests and data formatting and uploading into internal analysis systems. 
  • Troubleshooting basic procedural problems. 
  • Working in the lab with minimal supervision. 
  • Analyzing and interpreting data using a range of software tools and computational approaches. 
  • Participating in and contributing to scientific discussions, meetings, and presentations. 
  • Working on multiple projects, timelines, and priorities in parallel. 
  • Maintaining an updated and organized lab notebook according to company regulations. 

Skills/Knowledge Required: 

  • Bachelor’s degree in biology, biochemistry, neuroscience, or related field with at least 4 years of previous wet lab experience, industry experience preferred. (Do not submit PhD's.) 
  • Expertise in tissue culture, biochemistry, and molecular biology techniques. 
  • Experience performing immunocytochemistry and/or immunofluorescence assays, as well as microscopy and quantitation techniques, is a strong plus. 
  • Good record keeping for protocols and lab notebook. 

Other Attributes: 

  • Self-motivated to learn and contribute 
  • Demonstrated examples of both independent productivity and team-based interpersonal skills 
  • Enthusiasm for science, laboratory work, and drug discovery. 
  • Commitment to meeting timelines, robustness and rigor. 
  • Works efficiently.

For immediate consideration please send resumes to