Scientist I in Cambridge, MA at Apex Life Sciences

Date Posted: 4/4/2018

Job Snapshot

  • Employee Type:
    Full-Time
  • Location:
    Cambridge, MA
  • Job Type:
    Science
  • Experience:
    At least 3 year(s)
  • Date Posted:
    4/4/2018
  • Job ID:
    836941

Job Description


Duties: 
  • Responsible for developing larger scale quantitative proteomic approaches to identify and verify the differential expression of surface membrane proteins across the tumor tissues and understand their respective co-localized partners.
  • Perform affinity enrichment associated with proteomic approach to characterize and identify the interacting proteins, and elucidate mechanism of action for antibodies or small molecules which modulate drug targets.
Skills:
  • 3 years of experience in the area of biochemistry or bioanalytics 
  • Have in-depth knowledge of and hands-on experience with LC-MS/MS of proteins and peptides. 
  • Have ability to operate and maintain multiple mass spectrometry platforms (e.g. Orbitrap, Q-Exactive, Q-Trap mass spectrometers etc)
  • Strong experience in proteomics sample preparation for mass spectrometry, such as cells and tissue membrane extraction, immunoprecipitation, protein digestion and so on, and familiar with software for protein identification and validation.

Education: BS or MS degree in biological science or bioanalytical chemistry