MDI Research Scientist in City Center, NC at Apex Life Sciences

Date Posted: 2/28/2018

Job Snapshot

Job Description

Apex Life Sciences is looking for a Subject Matter Expert in Meter Dose Inhalations.

Relocation Assistance will be available!

 Please email your resume to

Our client is a leading CDMO (Contract Development and Manufacturing Organization). Our client has an outstanding reputation and expertise in the specialized fields of respiratory, topical and parenteral product development and analytical method development. Our client in RTP site offers analytical, preformulation, and formulation development services in these specialized fields. They are currently expanding its capabilities with the implementation of a new GMP suite that will produce clinical trial material for non-sterile dosage forms.

The Formulation Development department is involved in the development and manufacture of inhaled, topical, injectable, and nasal dosage forms. We are seeking a Research Scientist with experience in product development for these dosage forms, with specific expertise in pressurized metered dose inhalers (pMDI).

In this position, your key responsibilities will be to:

  • Represent the department as a subject matter expert in MDI product development, including reverse engineering, pre-formulation studies, formulation development, and product characterization.
  • Evaluate and select excipients and packaging components such as cans, valves, actuators, dose counters, and overwraps.
  • Work with the Manufacturing Department to develop and scale up MDI manufacturing processes.
  • Independently develop test methods, study protocols, and experimental designs.
  • Perform aerosol testing or product characterization in a supporting role.
  • Review laboratory notebooks and summarize results and trends in technical reports and presentations
  • Assist Business Development through preparation of proposals and work orders for customers.

Required Qualifications

  • Ph.D. with 2+ years of relevant industry experience or MS degree with 7+ years of relevant industry experience, with specialization in chemistry or the pharmaceutical sciences.
  • Proficient in aerosol characterization techniques, including cascade impaction (e.g. NGI), delivered dose uniformity, total can assay, foreign particulate matter, spray pattern, plume geometry, and Karl Fischer moisture analysis.
  • Strong written and oral communication skills for preparation of protocols, reports, and presentations.
  • Experience in working both independently and in a team-oriented, collaborative environment.
  • Experience with working in a cGMP environment. Preferred Qualifications
  • Experience in preformulation characterization with an understanding of the impact of drug physicochemical properties on formulation performance. Hands-on experience with formulation development and testing of injectable, nasal, and topical dosage forms.
  • Experience in fine particle generation (e.g. jet milling) and powder characterization (e.g. TGA, DSC, DVS, SEM, particle size by laser diffraction, etc).
  • Skilled in statistical design of experiments (DoE). Experience with JMP is a plus.

Please apply to this position by sending your resume to


EEO Employer

Apex is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at or 844-463-6178.