Biosample Operations Lab Technician I in South San Francisco, CA at Apex Life Sciences

Date Posted: 6/6/2018

Job Snapshot

Job Description


Duties: 

Sample Handling

  • Receives study samples via the receiving dept. and/or couriers into BRM Operations, including unpacking and checking of received samples.
  • Performs inventory of inbound shipments, logs samples into sample management databases and manages sample discrepancies as necessary, with support from BRM Project Support.
  • Ensures that samples are managed and stored according to protocol requirements and BRM Operations best practices.
  • Sets-up and prepares outbound shipping requests and related documents within agreed timelines, packs samples for dispatch according to the applicable transport regulations.
  • Organizes and tracks sample shipments to internal and external analytical laboratories, arranges for appropriate transport, liaises with Couriers or local shipping department, as appropriate.
  • Destroys samples in accordance with applicable guidelines on request.

Sample Processing
 

  • Performs manual and/or automated sample processing for serum/plasma/urine/DNA/RNA aliquoting.
  • Performs DNA/RNA isolation from various clinical sample types (Blood, Tissues, WBCs, plasma, saliva, urine) on a routine basis, according to timelines set by the Supervisor.
  • Performs in-process QC methods to assess quality of samples.
  • Maintains detailed laboratory records of samples QC steps and related quality data.
  • Supports the evaluation of novel technologies and techniques for their suitability for analyzing clinical samples.
  • Supports method development, qualification, and implementation of laboratory instruments.
  • Supports laboratory process optimization and validation.
  • Support experiments that address critical findings from analytical data anomalies that are potentially sample-related; participates in interpretation of results and authorship of final reports
     

General 

  • Follows appropriate GCP lab guidelines.
  • Works in accordance with all applicable Controlled Documents (e.g. SOPs, Working Instructions, Working Documents), as appropriate, to complete sample handling & processing activities and according to local health and safety rules.
  • Maintains a neat working environment in laboratory work areas.
  • Completes, files, and archives all relevant study documentation according to the applicable controlled documents.
  • Ensures that the BRM sample management databases are maintained up to date and are in accordance with the completed study activities and sample status.
  • Liaises with Project Support, as needed, to provide status updates on study related activities to BRM customers.
  • Coordinates with other BRM Operations staff on study related issues.
  • Escalates issues to local supervisor or Sr. BLA as appropriate, to obtain guidance and direction.
  • Supports the Lab Head and the Biosample Operations Lab Supervisor in implementing new processes, systems and SOPs/guidance.
  • Monitors freezers (e.g. temperature monitoring, issue logs, maintenance, freezer space & organization etc.)
  • Provides administrative support to the functioning of the lab, as appropriate (use of ordering system, manage consumables, maintain inventory lists etc.)

Skills: 

  • Experience, Skills, Knowledge Demonstrated experience working in a laboratory managing clinical or non-clinical samples.
  • Experience in utilizing a variety of analytical platforms and instrumentation Proficiency with PC computer systems, including email and calendar applications and MS Office.
  • Good organizational, multitasking, and prioritization skills.
  • Good written and oral communication skills.
  • Requires attention to detail, and accuracy in data entry, while maintaining study timelines.
  • Good analytical and problem solving skills, paired with partnering and performance skills.
  • Team player with demonstrated good interpersonal skills and an ability to build effective working relationships within functional area.
  • Demonstrated ability to work under pressure and to tight timelines.
  • Customer orientated mind-set.
  • Good level of initiative and the ability to work independently and with minimal supervision.
  • Good theoretical and practical understanding of nucleic acid handling and analysis.
  • Prior experience in DNA next generation sequencing (NGS).
  • Computer skills in laboratory informatics systems and data processing.
  • Experience working in multi-cultural teams

Education: 

  • Minimum: Associate Degree in science or equivalent recognized qualification and/or 1-2 years of experience in similar sample handling and processing laboratory environment.
  • Preferred: BS/MS with at least 3 years of experience in molecular biology technics applied in a pharmaceutical/biotech company.

Hours Per Day: 8.00