Associate Scientist in San Diego, CA at Apex Life Sciences

Date Posted: 6/5/2018

Job Snapshot

  • Employee Type:
    Full-Time
  • Location:
    San Diego, CA
  • Job Type:
    Science
  • Experience:
    Not Specified
  • Date Posted:
    6/5/2018
  • Job ID:
    855655

Job Description


The Biotherapeutics department is seeking a self-motivated, energetic, detail-oriented candidate with strong background in antibody-based drug discovery, molecular biology, and cell-based assays.

The focus of this position will be to utilize existing cloning techniques to establish a library display platform developed for antibody screening. The successful candidate will be responsible for evaluating novel biotherapeutics for drug candidate screening, lead optimization, and functional activities employing engineered or primary immune cell-based functional assays. The candidate should be highly effective in collaborating with internal team members and support any project teams when necessary. Strong problem solving and time management skills are essential to complete diverse assigned tasks.

CORE JOB FUNCTIONS:

  • Perform yeast display panning and screening for antibody discovery and optimization
  • Develop binding and functional assays and troubleshoot existing protocols with guidance
  • Routinely design and perform high quality and well controlled experiments with minimal supervision
  • Generate and independently analyze multi-parametric datasets using appropriate analytic programs
  • Effectively communicate results and findings to multi-disciplinary team
  • Maintain an accurate electronic notebook in a timely manner and comply with laboratory safety procedures

KNOWLEDGE/SKILLS/ABILITIES (KSA's):

  • Bachelor’s degree in a scientific discipline with at least 8 years work experience or Master’s degree with at least 6 years work experience of directly relevant biotechnology or pharmaceutical industry experience.
  • Experience with tissue culture of cell lines and generating stable overexpressing cell lines
  • Experience desired with standard techniques including flow cytometry, cytokine analysis, and ELISA, and molecular cloning
  • Familiar with formatting 96-well to High Throughput assay systems
  • Familiar with multi-parameters flow cytometry analysis (surface/intracellular staining, cell proliferation) using BD Canto, LifeTechnology Attune, or the BioRad S3e Cell Sorting System
  • Proficiency with FlowJo, Prism, Microsoft office applications • Proficiency in molecular biology laboratory techniques (i.e. cloning, transformations, transfections, Western blots)
  • Strong verbal presentation and written communication skills
  • Able to work and communicate effectively and collaboratively within the immediate group and supervisor
  • Team player, detail oriented and organized

For immediate consideration, please send resumes to khurlbut@apexlifesciences.com

#LI-KH2

EEO Employer

Apex is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystemsinc.com or 844-463-6178.